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KMID : 0383820110700020165
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Tuberculosis and Respiratory Diseases
2011 Volume.70 No. 2 p.165 ~ p.169
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A Case of Middle Mediastinal Malignant Paraganglioma
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Park Sung-Bum
Park Silvia
Bang Sun-Ha
Jeon Kyeong-Man
Koh Won-Jung
Suh Gee-Young
Chung Man-Pyo
Kim Ho-Joong
Kwon O-Jung
Ko Young Hyeh
Um Sang-Won
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Abstract
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Pheochromocytomas are neuroendocrine tumors of chromaffin cell that originate in the paraganglia of the adrenal medulla. Approximately 10% of pheochromocytomas are found in the extra-adrenal paraganglia and are called paragangliomas. However, cases of middle mediastinal paragangliomas are very rare. In this case, the patient presented with a voice change and a headache. A middle mediastinal soft tissue mass with marked enhancement was detected on computed tomography of the chest. The 24-hour urine catecholamine level was markedly elevated. The middle mediastinal mass was biopsied via mediastinoscopy and the resulting immunohistochemical staining was compatible with a diagnosis of middle mediastinal paraganglioma. The mass was resected surgically and the symptoms were relieved.
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KEYWORD
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Paraganglioma, Mediastinum, Neoplasms
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